Metformin Impedes Oxidation of LDL In Vitro

• Main Authors: Christine Rossmann (Author), Cornelia Ranz (Author), Gerd Kager (Author), Gerhard Ledinski (Author), Martin Koestenberger (Author), Willibald Wonisch (Author), Thomas Wagner (Author), Sebastian P. Schwaminger (Author), Bruno Di Geronimo (Author), Andelko Hrzenjak (Author), Seth Hallstöm (Author), Gilbert Reibnegger (Author), Gerhard Cvirn (Author), Margret Paar (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metformin is the most commonly prescribed glucose-lowering drug for the treatment of type 2 diabetes. The aim of this study was to investigate whether metformin is capable of impeding the oxidation of LDL, a crucial step in the development of endothelial dysfunction and atherosclerosis. LDL was oxid...