Can isepamicin be a potential option for extended spectrum beta-lactamases and carbapenemases expressing Escherichia coli?

• Main Authors: Yamuna Devi Bakthavatchalam (Author), Fiza Abdullah (Author), Devishree Srinivasan (Author), Ayyanraj Neeravi (Author), Rani Diana Sahni (Author), Abi Manesh (Author), Balaji Veeraraghavan (Author)
• Format: Book
• Published: Elsevier, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Beta-lactamase expressing Enterobacterales are challenging to treat. The potency of aminoglycosides as a bactericidal agent has increased interest in using them in combination regimens. In the present study, we evaluated the in-vitro activity of isepamicin and its comparator against phen...