CD36 deficiency ameliorates drug-induced acute liver injury in mice

• Main Authors: Chen Zhang (Author), Xiao Shi (Author), Zhongping Su (Author), Chao Hu (Author), Xianmin Mu (Author), Jinshun Pan (Author), Mengjing Li (Author), Fengmeng Teng (Author), Tao Ling (Author), Ting Zhao (Author), Che Xu (Author), Guozhong Ji (Author), Qiang You (Author)
• Format: Book
• Published: BMC, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Acetaminophen (APAP) overdose causes hepatotoxicity and even acute liver failure. Recent studies indicate that sterile inflammation and innate immune cells may play important roles in damage-induced hepatocytes regeneration and liver repair. The scavenger receptor CD36 has its cr...