Synthesis and In Vitro Cytotoxicity of the 4-(Halogenoanilino)-6-bromoquinazolines and Their 6-(4-Fluorophenyl) Substituted Derivatives as Potential Inhibitors of Epidermal Growth Factor Receptor Tyrosine Kinase

Series of the 2-unsubstituted and 2-(4-chlorophenyl)-substituted 4-anilino-6-bromoquinazolines and their 6-(4-fluorophenyl)-substituted derivatives were evaluated for in vitro cytotoxicity against MCF-7 and HeLa cells. The 2-unsubstituted 4-anilino-6-bromoquinazolines lacked activity, whereas most o...

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Main Authors: Malose Jack Mphahlele (Author), Hugues K. Paumo (Author), Yee Siew Choong (Author)
Format: Book
Published: MDPI AG, 2017-11-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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