Health benefits, costs, and cost-effectiveness of earlier eligibility for adult antiretroviral therapy and expanded treatment coverage: a combined analysis of 12 mathematical models

• Main Authors: Jeffrey W Eaton, PhD (Author), Nicolas A Menzies, MPH (Author), John Stover, MA (Author), Valentina Cambiano, MS (Author), Leonid Chindelevitch, PhD (Author), Anne Cori, PhD (Author), Jan A C Hontelez, PhD (Author), Salal Humair, PhD (Author), Cliff C Kerr, PhD (Author), Daniel J Klein, PhD (Author), Sharmistha Mishra, MD (Author), Kate M Mitchell, PhD (Author), Brooke E Nichols, MS (Author), Prof. Peter Vickerman, DPhil (Author), Roel Bakker, PhD (Author), Till Bärnighausen, DSc (Author), Anna Bershteyn, PhD (Author), Prof. David E Bloom, PhD (Author), Marie-Claude Boily, PhD (Author), Stewart T Chang, PhD (Author), Ted Cohen, DPH (Author), Peter J Dodd, PhD (Author), Prof. Christophe Fraser, PhD (Author), Chaitra Gopalappa, PhD (Author), Prof. Jens Lundgren, DMSc (Author), Natasha K Martin, DPhil (Author), Evelinn Mikkelsen, MSc (Author), Elisa Mountain, MSc (Author), Quang D Pham, MD (Author), Michael Pickles, PhD (Author), Prof. Andrew Phillips, PhD (Author), Lucy Platt, PhD (Author), Carel Pretorius, PhD (Author), Holly J Prudden, MSc (Author), Prof. Joshua A Salomon, PhD (Author), David A M C van de Vijver, PhD (Author), Sake J de Vlas, PhD (Author), Bradley G Wagner, PhD (Author), Richard G White, PhD (Author), David P Wilson, PhD (Author), Lei Zhang, PhD (Author), John Blandford, PhD (Author), Gesine Meyer-Rath, PhD (Author), Michelle Remme, MSc (Author), Paul Revill, PhD (Author), Nalinee Sangrujee, PhD (Author), Fern Terris-Prestholt, PhD (Author), Meg Doherty, PhD (Author), Nathan Shaffer, MD (Author), Prof. Philippa J Easterbrook, MD (Author), Gottfried Hirnschall, MD (Author), Prof. Timothy B Hallett, PhD (Author)
• Format: Book
• Published: Elsevier, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: New WHO guidelines recommend initiation of antiretroviral therapy for HIV-positive adults with CD4 counts of 500 cells per μL or less, a higher threshold than was previously recommended. Country decision makers have to decide whether to further expand eligibility for antiretroviral thera...