Surface molecules of extracellular vesicles secreted by the helminth pathogen Fasciola hepatica direct their internalisation by host cells.

• Main Authors: Eduardo de la Torre-Escudero (Author), Jared Q Gerlach (Author), Adam P S Bennett (Author), Krystyna Cwiklinski (Author), Heather L Jewhurst (Author), Kathryn M Huson (Author), Lokesh Joshi (Author), Michelle Kilcoyne (Author), Sandra O'Neill (Author), John P Dalton (Author), Mark W Robinson (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Helminth parasites secrete extracellular vesicles (EVs) that can be internalised by host immune cells resulting in modulation of host immunity. While the molecular cargo of EVs have been characterised in many parasites, little is known about the surface-exposed molecules that participate in ligand-r...