The teratogenic effect of pregabalin on heart, liver and kidney in rats: a light microscopic, electron microscopic and immunohistochemical study

• Main Authors: Omnia I. Ismail (Author), Eman S. Shaltout (Author), Nora Z. Abdellah (Author), Diab F. Hetta (Author), Wael M. A. Abd El-Ghani (Author), Lobna A. Abdelzaher (Author), Ahmed Mohamed Mohamed Mahmoud (Author), Asmaa M. Hasan (Author), Noha A. Rashed (Author), Noha Esmael Ebrahem (Author)
• Format: Book
• Published: BMC, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Pregabalin (PGB) was approved as new anti-epileptic drugs with little information about its teratogenic effect. Aim of the work to evaluate the developmental toxicity of PGB. Materials and methods 60 pregnant albino rats were divided into three groups. PGB (500 mg/kg body weight/...