Viscous Core Liposomes Increase siRNA Encapsulation and Provides Gene Inhibition When Slightly Positively Charged

• Main Authors: Shayan Ahmed (Author), Hugo Salmon (Author), Nicholas Distasio (Author), Hai Doan Do (Author), Daniel Scherman (Author), Khair Alhareth (Author), Maryam Tabrizian (Author), Nathalie Mignet (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Since its discovery, evidence that siRNA was able to act as an RNA interference effector, led to its acceptation as a novel medicine. The siRNA approach is very effective, due to its catalytic mechanism, but still the limitations of its cellular delivery should be addressed. One promising form of no...