Microsatellite instability and mismatch repair protein deficiency: equal predictive markers?

• Main Authors: Maja L. Nádorvári (Author), Gábor Lotz (Author), Janina Kulka (Author), András Kiss (Author), József Tímár (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Current clinical guidelines recommend mismatch repair (MMR) protein immunohistochemistry (IHC) or molecular microsatellite instability (MSI) tests as predictive markers of immunotherapies. Most of the pathological guidelines consider MMR protein IHC as the gold standard test to identify cancers with...