Curative Effect of AD-MSCs against Cisplatin-Induced Hepatotoxicity in Rats is Potentiated by Azilsartan: Targeting Oxidative Stress, MAPK, and Apoptosis Signaling Pathways

• Main Authors: Amany Abdlrehim Bekhit (Author), Olivia N. Beshay (Author), Michael A. Fawzy (Author), Sara Mohamed Naguib Abdel-Hafez (Author), Gaber El-Saber Batiha (Author), Farid S. Ataya (Author), Moustafa Fathy (Author)
• Format: Book
• Published: Hindawi Limited, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Despite its clinical value, cisplatin (CISP) is complicated by marked hepatotoxicity via inducing oxidative stress, inflammatory, and apoptotic pathways. This study aims to explore the protective impact of azilsartan (AZIL), an antihypertensive drug, in addition to adipose tissue-derived mesenchymal...