Characterization of microminipig as a laboratory animal for pharmacological study by analyzing bepridil-induced cardiovascular responses

• Hlavní autoři: Yoshio Nunoi (Autor), Mihoko Hagiwara-Nagasawa (Autor), Ryuichi Kambayashi (Autor), Ai Goto (Autor), Koki Chiba (Autor), Takeshi Wada (Autor), Hiroko Izumi-Nakaseko (Autor), Akio Matsumoto (Autor), Yoshinori Watanabe (Autor), Atsushi Sugiyama (Autor)
• Médium: Kniha
• Vydáno: Elsevier, 2020-05-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Since microminipig is becoming attractive model for various cardiac electropharmacological applications, which may meet consideration of 3Rs. We characterized microminipigs by analyzing how multi-ionic channel inhibitor bepridil may affect their in situ hearts in comparison with dogs. Bepridil in do...