Characterization of microminipig as a laboratory animal for pharmacological study by analyzing bepridil-induced cardiovascular responses

• Main Authors: Yoshio Nunoi (Author), Mihoko Hagiwara-Nagasawa (Author), Ryuichi Kambayashi (Author), Ai Goto (Author), Koki Chiba (Author), Takeshi Wada (Author), Hiroko Izumi-Nakaseko (Author), Akio Matsumoto (Author), Yoshinori Watanabe (Author), Atsushi Sugiyama (Author)
• Format: Book
• Published: Elsevier, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Since microminipig is becoming attractive model for various cardiac electropharmacological applications, which may meet consideration of 3Rs. We characterized microminipigs by analyzing how multi-ionic channel inhibitor bepridil may affect their in situ hearts in comparison with dogs. Bepridil in do...