Pharmacokinetics and Pharmacodynamics of Cefepime in Adults with Hematological Malignancies and Febrile Neutropenia after Chemotherapy

• Main Authors: José C. Álvarez (Author), Sonia I. Cuervo (Author), Edelberto Silva (Author), Jorge A. Díaz (Author), Lorena L. Jiménez (Author), Daniel S. Parra (Author), Julio C. Gómez (Author), Ricardo Sánchez (Author), Jorge A. Cortés (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Patients with chemotherapy-induced febrile neutropenia (CIFN) may have changes in the pharmacokinetics (PK) compared to patients without malignancies or neutropenia. Those changes in antibiotic PK could lead to negative outcomes for patients if the therapy is not adequately adjusted to this. In this...