Antiemetic Activity of FK1052, a 5-HT3- and 5-HT4-Receptor Antagonist, in Suncus murinus and Ferrets

• Główni autorzy: Hiroe Nakayama (Autor), Hisashi Yamakuni (Autor), Mika Higaki (Autor), Hirofumi Ishikawa (Autor), Katsunori Imazumi (Autor), Masahiko Matsuo (Autor), Seitaro Mutoh (Autor)
• Format: Książka
• Wydane: Elsevier, 2005-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

We investigated the effect of FK1052 [(+)-8,9-dihydro-10-methyl-7-[(5-methyl-1H-imidazol-4-yl)methyl]pyrido[1,2-a]indol-6(7H)-one hydrochloride], a 5-HT3- and 5-HT4-receptor antagonist, on the emesis induced by motion stimuli, copper sulfate, or cisplatin in either Suncus murinus or ferrets and also...