Human Cardiospheres as a Source of Multipotent Stem and Progenitor Cells

• Main Authors: Lucio Barile (Author), Mihaela Gherghiceanu (Author), Laurenţiu M. Popescu (Author), Tiziano Moccetti (Author), Giuseppe Vassalli (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cardiospheres (CSs) are self-assembling multicellular clusters from the cellular outgrowth from cardiac explants cultured in nonadhesive substrates. They contain a core of primitive, proliferating cells, and an outer layer of mesenchymal/stromal cells and differentiating cells that express cardiomyo...