Serine and glycine metabolism-related gene expression signature stratifies immune profiles of brain gliomas, and predicts prognosis and responses to immunotherapy

• Main Authors: Siliang Chen (Author), Shuxin Zhang (Author), Wentao Feng (Author), Junhong Li (Author), Yunbo Yuan (Author), Wenhao Li (Author), Zhihao Wang (Author), Yuan Yang (Author), Yanhui Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glioma is one of the most lethal cancers and causes more than 200,000 deaths every year. Immunotherapy was an inspiring therapy for multiple cancers but failed in glioma treatment. The importance of serine and glycine and their metabolism has been well-recognized in the physiology of immune cells an...