Application of quantitative protein mass spectrometric data in the early predictive analysis of membrane-bound target engagement by monoclonal antibodies

ABSTRACTModel-informed drug discovery advocates the use of mathematical modeling and simulation for improved efficacy in drug discovery. In the case of monoclonal antibodies (mAbs) against cell membrane antigens, this requires quantitative insight into the target tissue concentration levels. Protein...

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Main Authors: Armin Sepp (Author), Morris Muliaditan (Author)
Format: Book
Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
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3rd Floor Main Library

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