Role of oxidative and nitrosative stress in pathophysiology of toxic epidermal necrolysis and Stevens Johnson syndrome-A pilot study

• Main Authors: Dincy Peter (Author), G Jayakumar Amirtharaj (Author), Teena Mathew (Author), Susanne Pulimood (Author), Anup Ramachandran (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Oxidative and nitrosative stress caused by drug metabolism may be a trigger for keratinocyte apoptosis in the epidermis seen in toxic epidermal necrolysis (TEN) and Stevens Johnson syndrome (SJS). Aims: To estimate oxidative damage in the serum and to examine the role of nitric oxide in...