Transdermal delivery of colchicine using dissolvable microneedle arrays for the treatment of acute gout in a rat model
Colchicine (Col) is used to prevent and treat acute gout flare; however, its therapeutic use is strictly limited owing to severe gastrointestinal side effects after oral administration. Therefore, we developed a dissolvable Col-loaded microneedle (MN) with hyaluronic acid to deliver Col via the tran...
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Main Authors: | Yang Liu (Author), Xiaoruo Zhu (Author), Shiliang Ji (Author), Zhen Huang (Author), Yuhui Zang (Author), Ying Ding (Author), Junfeng Zhang (Author), Zhi Ding (Author) |
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Format: | Book |
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Taylor & Francis Group,
2022-12-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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