Concanavalin A promotes angiogenesis and proliferation in endothelial cells through the Akt/ERK/Cyclin D1 axis

• Main Authors: Jing-Zhou Li (Author), Xiao-Xia Zhou (Author), Wei-Yin Wu (Author), Hai-Feng Qiang (Author), Guo-Sheng Xiao (Author), Yan Wang (Author), Gang Li (Author)
• Format: Book
• Published: Taylor & Francis Group, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Concanavalin A (Con A) exhibited multiple roles in cancer cells. However, the role of Con A in endothelial cells was not reported. Objective Our present study investigated the potential angiogenic role of Con A in endothelial cells and ischaemic hind-limb mice. Materials and methods Human um...