Triolein emulsion enhances temozolomide brain delivery: an experimental study in rats

• Main Authors: Won-Bae Seung (Author), Seung Heon Cha (Author), Hak Jin Kim (Author), Seon Hee Choi (Author), Juho Lee (Author), Dongmin Kwak (Author), Hyunwoo Kim (Author), Jin-Wook Yoo (Author), Yong-Woo Kim (Author), Sang Kyoon Kim (Author), Da-Sol Lee (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose To evaluate the enhancement of temozolomide (TMZ) delivery in the rat brain using a triolein emulsion. Materials and Methods Rats were divided into the five groups as following: group 1 (negative control), group 2 (treated with triolein emulsion and TMZ 20 mg/kg), and group 3 (TMZ 20 mg/kg t...