Strategic application of CuAAC click chemistry in the modification of natural products for anticancer activity

• Hoofdauteurs: Zaozao Xiao (Auteur), Yuang Gu (Auteur), Hewei Dong (Auteur), Bo Liu (Auteur), Weiwei Jin (Auteur), Jie Li (Auteur), Peixiang Ma (Auteur), Hongtao Xu (Auteur), Wei Hou (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2023-12-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Natural products play a key role in the history of human drug discovery, and especially for the anticancer agents. Copper(I)-catalyzed alkyne-azide [3+2] cycloaddition (CuAAC) reaction is perhaps the most powerful method for the efficient modification of complex natural products, enabling the direct...