Risk of major depressive increases with increasing frequency of alcohol drinking: a bidirectional two-sample Mendelian randomization analysis

• Main Authors: Weiyu Feng (Author), Bing Zhang (Author), Pengyu Duan (Author), Yong-hong Bi (Author), Zhehao Jin (Author), Xiaoyan Li (Author), Xiangcheng Zhao (Author), Kun Zuo (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

IntroductionA growing body of evidence suggests that alcohol use disorders coexist with depression. However, the causal relationship between alcohol consumption and depression remains a topic of controversy.MethodsWe conducted a two-sample two-way Mendelian randomization analysis using genetic varia...