The role of CYP1A1/2 in cholesterol ester accumulation provides a new perspective for the treatment of hypercholesterolemia

• Main Authors: Jian Lu (Author), Xuyang Shang (Author), Bingyi Yao (Author), Dongyi Sun (Author), Jie Liu (Author), Yuanjin Zhang (Author), He Wang (Author), Jingru Shi (Author), Huaqing Chen (Author), Tieliu Shi (Author), Mingyao Liu (Author), Xin Wang (Author)
• Format: Book
• Published: Elsevier, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cholesterol is an important precursor of many endogenous molecules. Disruption of cholesterol homeostasis can cause many pathological changes, leading to liver and cardiovascular diseases. CYP1A is widely involved in cholesterol metabolic network, but its exact function has not been fully elucidated...