Computational Development of Inhibitors of Plasmid-Borne Bacterial Dihydrofolate Reductase
Resistance to trimethoprim and other antibiotics targeting dihydrofolate reductase may arise in bacteria harboring an atypical, plasmid-encoded, homotetrameric dihydrofolate reductase, called R67 DHFR. Although developing inhibitors to this enzyme may be expected to be promising drugs to fight trime...
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| Format: | Book |
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MDPI AG,
2022-06-01T00:00:00Z.
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A1234.567 |
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