TFAP2C-Activated MALAT1 Modulates the Chemoresistance of Docetaxel-Resistant Lung Adenocarcinoma Cells

• Main Authors: Jing Chen (Author), Xiaobei Liu (Author), Yichen Xu (Author), Kai Zhang (Author), Jiayuan Huang (Author), Banzhou Pan (Author), Dongqin Chen (Author), Shiyun Cui (Author), Haizhu Song (Author), Rui Wang (Author), Xiaoyuan Chu (Author), Xiaoli Zhu (Author), Longbang Chen (Author)
• Format: Book
• Published: Elsevier, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chemoresistance remains a great obstacle in effective lung adenocarcinoma (LUAD) treatment. Previously, we verified the role of microRNA-200b (miR-200b) in the formation of docetaxel (DTX)-resistant LUAD cells. This study aims to investigate the mechanism underlying the low level of miR-200b in DTX-...