Characterization and distribution of niosomes containing ursolic acid coated with chitosan layer

• Main Authors: Andang Miatmoko (Author), Shofi Ameliah Safitri (Author), Fayruz Aquila (Author), Devy Maulidya Cahyani (Author), Berlian Sarasitha Hariawan (Author), Eryk Hendrianto (Author), Esti Hendradi (Author), Retno Sari (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and purpose: Ursolic acid (UA) exhibits anti-hepatocarcinoma and hepatoprotective activities, thus promising as an effective oral cancer therapy. However, its poor solubility and permeability lead to low oral bioavailability. In this study, we evaluated the effect of different ratios of S...