Hemin Improves Insulin Sensitivity in Skeletal Muscle in High Fat-Fed Mice

• Main Authors: Tae-Jin Ju (Author), Woo-Young Kwon (Author), Yong-Woon Kim (Author), Jong-Yeon Kim (Author), Yong-Dae Kim (Author), In-Kyu Lee (Author), So-Young Park (Author)
• Format: Book
• Published: Elsevier, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract.: The present study examined whether hemin could prevent the development of high-fat diet-induced insulin resistance in the liver and skeletal muscle using a hyperinsulinemic-euglycemic clamp. A four-week high-fat feeding to mice increased the body weight, fat mass, and plasma levels of ins...