Modifying miRs for effective reprogramming of fibroblasts to cardiomyocytes

• Main Authors: Xinghua Wang (Author), Syeda S. Baksh (Author), Richard E. Pratt (Author), Victor J. Dzau (Author), Conrad P. Hodgkinson (Author)
• Format: Book
• Published: Elsevier, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Reprogramming scar fibroblasts into cardiomyocytes has been proposed to reverse the damage associated with myocardial infarction. However, the limited improvement in cardiac function calls for enhanced strategies. We reported enhanced efficacy of our miR reprogramming cocktail miR combo (miR-1, miR-...