Daily administration of yokukansan and keishito prevents social isolation-induced behavioral abnormalities and down-regulation of phosphorylation of neuroplasticity-related signaling molecules in mice

• Egile Nagusiak: Hironori Fujiwara (Egilea), Yaoyu Han (Egilea), Ken Ebihara (Egilea), Suresh Awale (Egilea), Ryota Araki (Egilea), Takeshi Yabe (Egilea), Kinzo Matsumoto (Egilea)
• Formatua: Liburua
• Argitaratua: BMC, 2017-04-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract Background Our previous studies demonstrated that post-weaning social isolation (ISO) in mice induces behavior abnormalities such as deficits of sociability- and attention-like behaviors. These deficits can be attenuated by methylphenidate (MPH), a drug used for attention deficit hyperactiv...