Prevalence of glucose 6-phosphate dehydrogenase deficiency in highly malaria-endemic municipalities in the Brazilian Amazon: A region-wide screening study

• Main Authors: Joabi Rocha Nascimento (Author), Jose Diego Brito-Sousa (Author), Anne Cristine Gomes Almeida (Author), Marly M Melo (Author), Monica Regina Farias Costa (Author), Laila Rowena Albuquerque Barbosa (Author), Reinaldo Nery Ramos (Author), Alexandre Vilhena Silva-Neto (Author), Patricia Carvalho da Silva Balieiro (Author), Erick Frota Gomes Figueiredo (Author), Emanuelle Lira Silva (Author), Djane Clarys Baia- (Author), Quique Bassat (Author), Gustavo Romero (Author), Gisely Cardoso Melo (Author), Vanderson Souza Sampaio (Author), Marcus Lacerda (Author), Wuelton Monteiro (Author)
• Format: Book
• Published: Elsevier, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Summary: Background: Difficulties associated with the assessment of glucose-6-phosphate dehydrogenase deficiency (G6PDd), particularly in remote areas, hinders the safe use of 8-aminoquinolines such as primaquine (PQ) and tafenoquine against Plasmodium vivax malaria due to the risk of haemolysis. Me...