The ubiquitin-conjugating enzyme CDC34 is essential for cytokinesis in contrast to putative subunits of a SCF complex in Trypanosoma brucei.

• Главные авторы: Federico Rojas (Автор), Joanna Koszela (Автор), Jacqueline Búa (Автор), Briardo Llorente (Автор), Richard Burchmore (Автор), Manfred Auer (Автор), Jeremy C Mottram (Автор), María Teresa Téllez-Iñón (Автор)
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• Опубликовано: Public Library of Science (PLoS), 2017-06-01T00:00:00Z.
• Предметы: article
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The ubiquitin-proteasome system is a post-translational regulatory pathway for controlling protein stability and activity that underlies many fundamental cellular processes, including cell cycle progression. Target proteins are tagged with ubiquitin molecules through the action of an enzymatic casca...