Effect of asfotase alfa in the treatment of hypophosphatasia- A systematic review

• Main Authors: N Jaswanthi (Author), R Sindhu (Author), P Nimmy (Author), D Prabu (Author), M RajMohan (Author), V V Bharathwaj (Author), Dinesh Dhamodhar (Author), S Sathiyapriya (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hypophosphatasia (HPP) is a life-threatening disease that occurs due to the mutation of the TNSALP (Tissue nonspecific isoenzyme of alkaline phosphatase) encoding gene. There is no approved treatment for Hypophosphatasia. Therefore, the only effective treatment for HPP is enzyme replacement therapy...