Pneumococcal Surface Protein A-Hybrid Nanoparticles Protect Mice from Lethal Challenge after Mucosal Immunization Targeting the Lungs

• Autori principali: Douglas Borges de Figueiredo (Autore), Kan Kaneko (Autore), Tasson da Costa Rodrigues (Autore), Ronan MacLoughlin (Autore), Eliane Namie Miyaji (Autore), Imran Saleem (Autore), Viviane Maimoni Gonçalves (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2022-06-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Pneumococcal disease remains a global burden, with current conjugated vaccines offering protection against the common serotype strains. However, there are over 100 serotype strains, and serotype replacement is now being observed, which reduces the effectiveness of the current vaccines. Pneumococcal...