Facile one-pot four-component synthesis of 3,4-dihydro-2-pyridone derivatives: Novel urease inhibitor scaffold

• Autori principali: Arash Modarres Hakimi (Autore), Negar Lashgari (Autore), Shabnam Mahernia (Autore), Ghodsi Mohammadi Ziarani (Autore), Massoud Amanlou (Autore)
• Natura: Libro
• Pubblicazione: Wolters Kluwer Medknow Publications, 2017-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

In the current study, a series of 3,4-dihydro-2-pyridone derivatives were synthesized in a one-pot four- component reaction of Meldrum's acid, benzaldehyde derivatives, methyl acetoacetate, and ammonium acetate. SiO2-Pr-SO3H was used as an efficient catalyst for the synthesis of the target comp...