Microfluidics-based immunofluorescence for fast staining of ALK in lung adenocarcinoma

• Main Authors: Saška Brajkovic (Author), Benjamin Pelz (Author), Maria-Giuseppina Procopio (Author), Anne-Laure Leblond (Author), Grégoire Repond (Author), Ariane Schaub-Clerigué (Author), Diego G Dupouy (Author), Alex Soltermann (Author)
• Format: Book
• Published: BMC, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Anaplastic lymphoma kinase (ALK) is a key oncogenic driver in lung adenocarcinoma patients and its fusion proteins are routinely assessed. The microfluidic tissue processor (MTP) device is based on a chip-confined low-volume technology allowing for rapid immunohistochemistry/immu...