The association of MEFV gene mutations with the disease risk and severity of systemic juvenile idiopathic arthritis

• Autors principals: Linqing Zhong (Autor), Wei Wang (Autor), Ji Li (Autor), Mingsheng Ma (Autor), Lijuan Gou (Autor), Changyan Wang (Autor), Zhongxun Yu (Autor), Tiannan Zhang (Autor), Yanqing Dong (Autor), Qijiao Wei (Autor), Hongmei Song (Autor)
• Format: Llibre
• Publicat: BMC, 2020-05-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Abstract Background Systemic juvenile idiopathic arthritis (sJIA) has many clinical features overlapping with familial Mediterranean fever (FMF), which is caused by mutations in MEFV gene. And FMF patients were easily misdiagnosed as sJIA in China. So we speculate that MEFV is critical genetic backg...