Newborn Screening for Primary Immune Deficiencies with a TREC/KREC/ACTB Triplex Assay-A Three-Year Pilot Study in Sweden

• Main Authors: Rolf H. Zetterström (Author), Michela Barbaro (Author), Annika Ohlsson (Author), Stephan Borte (Author), Susanne Jonsson (Author), Jacek Winiarski (Author), Ulrika von Döbeln (Author), Lennart Hammarström (Author)
• Format: Book
• Published: MDPI AG, 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Screening newborns for severe combined immunodeficiency (SCID) has become essential, since efficient methods to identify infants with these disorders exist and early stem cell transplantation is life-saving. Method: We performed a three-year screening trial in Stockholm comprised of 89,4...