The val¹⁵⁸met polymorphism of human catechol-O-methyltransferase (<it>COMT</it>) affects anterior cingulate cortex activation in response to painful laser stimulation

• Main Authors: Musso Francesco (Author), Warbrick Tracy (Author), Steffens Michael (Author), Toliat Mohammad R (Author), Thiele Holger (Author), Brinkmeyer Juergen (Author), Mobascher Arian (Author), Wittsack Hans-Joerg (Author), Saleh Andreas (Author), Schnitzler Alfons (Author), Winterer Georg (Author)
• Format: Book
• Published: SAGE Publishing, 2010-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Pain is a complex experience with sensory, emotional and cognitive aspects. Genetic and environmental factors contribute to pain-related phenotypes such as chronic pain states. Genetic variations in the gene coding for catechol-O-met...