Tissue distribution and abuse potential of prucalopride: findings from non-clinical and clinical studies
Background: Prucalopride is a selective serotonin type 4 (5-HT4) receptor agonist indicated for treatment of chronic idiopathic constipation (CIC) in adults (2 mg orally, daily). 5-HT4 receptors are present in the central nervous system; therefore, non-clinical and clinical assessments were performe...
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BioExcel Publishing Ltd,
2023-02-01T00:00:00Z.
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