MicroRNA-10a-5p regulates macrophage polarization and promotes therapeutic adipose tissue remodeling

• Main Authors: Yoon Keun Cho (Author), Yeonho Son (Author), Sang-Nam Kim (Author), Hyun-Doo Song (Author), Minsu Kim (Author), Ji-Hyun Park (Author), Young-Suk Jung (Author), Sang-Yeop Ahn (Author), Abhirup Saha (Author), James G. Granneman (Author), Yun-Hee Lee (Author)
• Format: Book
• Published: Elsevier, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: This study investigated the role of microRNAs generated from adipose tissue macrophages (ATMs) during adipose tissue remodeling induced by pharmacological and nutritional stimuli. Methods: Macrophage-specific Dicer knockout (KO) mice were used to determine the roles of microRNA generated...