Acidic/hypoxia dual-alleviated nanoregulators for enhanced treatment of tumor chemo-immunotherapy

• Main Authors: Xiaoju Guo (Author), Xiaoxiao Chen (Author), Jiayi Ding (Author), Feng Zhang (Author), Shunyang Chen (Author), Xin Hu (Author), Shiji Fang (Author), Lin Shen (Author), Chenying Lu (Author), Zhongwei Zhao (Author), Jianfei Tu (Author), Gaofeng Shu (Author), Minjiang Chen (Author), Jiansong Ji (Author)
• Format: Book
• Published: Elsevier, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chemotherapy plays a crucial role in triple-negative breast cancer (TNBC) treatment as it not only directly kills cancer cells but also induces immunogenic cell death. However, the chemotherapeutic efficacy was strongly restricted by the acidic and hypoxic tumor environment. Herein, we have successf...