Lipophilicity, Pharmacokinetic Properties, and Molecular Docking Study on SARS-CoV-2 Target for Betulin Triazole Derivatives with Attached 1,4-Quinone

• Asıl Yazarlar: Monika Kadela-Tomanek (Yazar), Maria Jastrzębska (Yazar), Krzysztof Marciniec (Yazar), Elwira Chrobak (Yazar), Ewa Bębenek (Yazar), Stanisław Boryczka (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2021-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

A key parameter in the design of new active compounds is lipophilicity, which influences the solubility and permeability through membranes. Lipophilicity affects the pharmacodynamic and toxicological profiles of compounds. These parameters can be determined experimentally or by using different calcu...