Hearing impairment and vestibular function in patients with a pathogenic splice variant in the LHX3 gene

• Main Authors: Åsa Kjellgren (Author), Elenor Lundgren (Author), Irina Golovleva (Author), Berit Kriström (Author), Mimmi Werner (Author)
• Format: Book
• Published: BMC, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background LHX3 is a gene encoding a LIM-homeodomain transcription factor important for the fetal development of several organs, such as the pituitary gland, spinal motor neurons and the inner ear. Pathogenic and likely pathogenic variants in the LHX3 gene are infrequent and result in a rar...