Pre-clinical drug-drug interactions (DDIs) of gefitinib with/without losartan and selective serotonin reuptake inhibitors (SSRIs): citalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, and venlafaxine

Objective: To evaluate drug-drug interactions (DDIs) between gefitinib with/without losartan and selective serotonin reuptake inhibitors (SSRIs). Methods: In vitro supersomes were used to identify CYP isoenzymes (CYP1A2, 2C9, 2C19, 2D6, and 3A4) involved in drug metabolism, and in vitro pooled cryop...

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Main Authors: Thu-Lan T. Luong (Author), Chelsea N. Powers (Author), Brian J. Reinhardt (Author), Peter J. Weina (Author)
Format: Book
Published: Elsevier, 2022-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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