Propagation of Fibrillar Structural Forms in Proteins Stopped by Naturally Occurring Short Polypeptide Chain Fragments

• Main Authors: Irena Roterman (Author), Mateusz Banach (Author), Leszek Konieczny (Author)
• Format: Knjiga
• Izdano: MDPI AG, 2017-11-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Amyloids characterized by unbounded growth of fibrillar structures cause many pathological processes. Such unbounded propagation is due to the presence of a propagating hydrophobicity field around the fibril's main axis, preventing its closure (unlike in globular proteins). Interestingly, simil...