Roles of integrin-linked kinase in cell signaling and its perspectives as a therapeutic target

Integrin-linked kinase (ILK) localizes to focal adhesions, and interacts with the cytoplasmic tail of β subunits of integrins and couples them to the actin cytoskeleton. ILK may act as a kinase and transmit the signals in a phosphatidylinositol 3-kinase-dependent manner, or can act as a scaffold pro...

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Main Authors: Chih-Feng Yen (Author), Hsin-Shih Wang (Author), Chyi-Long Lee (Author), Shuen-Kuei Liao (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2014-08-01T00:00:00Z.
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