Pharmacological interventions for preventing opioid-induced hyperalgesia in adults after opioid-based anesthesia: a systematic review and network meta-analysis

• Ngā kaituhi matua: Wei-Ji Xie (Author), Ji-Shuang Hong (Author), Cheng-Fei Feng (Author), Hao-Feng Chen (Author), Wei Li (Author), Yong-Chun Li (Author)
• Hōputu: Pukapuka
• I whakaputaina: Frontiers Media S.A., 2023-06-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Background: Opioid-induced hyperalgesia (OIH) is an adverse event of prolonged opioid use that increases pain intensity. The optimal drug to prevent these adverse effects is still unknown. We aimed to conduct a network meta-analysis to compare different pharmacological interventions for preventing t...