Enhanced In Vitro Antitumor Activity of GnRH-III-Daunorubicin Bioconjugates Influenced by Sequence Modification

Enhanced In Vitro Antitumor Activity of GnRH-III-Daunorubicin Bioconjugates Influenced by Sequence Modification

Receptors for gonadotropin releasing hormone (GnRH) are highly expressed in various human cancers including breast, ovarian, endometrial, prostate and colorectal cancer. Ligands like human GnRH-I or the sea lamprey analogue GnRH-III represent a promising approach for the development of efficient dru...

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Main Authors: Sabine Schuster (Author), Beáta Biri-Kovács (Author), Bálint Szeder (Author), László Buday (Author), János Gardi (Author), Zsuzsanna Szabó (Author), Gábor Halmos (Author), Gábor Mező (Author)
Format: Book
Published: MDPI AG, 2018-11-01T00:00:00Z.
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