Imatinib inhibits migration of normal human epidermal melanocytes and suppress the phosphorylation of C-kit

• Main Authors: Jian-Xin Xia (Author), Fu-Qiu Li (Author), Kazunori Urabe (Author), Jin-Feng Wang (Author), Masutaka Furue (Author)
• Format: Book
• Published: Bangladesh Pharmacological Society, 2012-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To investigate the inhibitory effect of imatinib on the migration of normal human epidermal melanocytes (NHEM), the growth and differentiation of NHEM were measured by MTT assay. Transwell Cell Migration Assay was performed to determine the migration of NHEM following imatinib treatment. The phospho...