Adenine and benzimidazole-based mimics of REP-3123 as antibacterial agents against Clostridium difficile and Bacillus anthracis: Design, synthesis and biological evaluation

As part of our ongoing research efforts to develop new antibacterial agents acting on novel molecular targets, a series of twenty-two adenine and benzimidazole-based mimics of the lead compound REP-3123 was designed to target methionyl-tRNA synthetase of Clostridium difficile and Bacillus anthracis...

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Main Authors: Ahmed G. Eissa (Author), James A. Blaxland (Author), Rhodri O. Williams (Author), Kamel A. Metwally (Author), Sobhy M. El-Adl (Author), El-Sayed M. Lashine (Author), Leslie W.J. Baillie (Author), Claire Simons (Author)
Format: Book
Published: Faculty of Pharmacy, Cairo University, 2016-12-01T00:00:00Z.
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